What is one of the clinical signs of Kuru?

Kuru is a neurodegenerative condition historically associated with prion infections, most notably observed in the Fore people of Papua New Guinea. One of the hallmark clinical signs of Kuru is a distinct form of tremor or loss of motor control, often leading to the inability to coordinate movements. While headache is not the most recognizable symptom, it can occur as part of the overall experience of the disease, especially during the later stages or as an accompanying symptom due to the neurological decline.

Kuru also presents acute behavioral changes, as well as tremors and eventual loss of the ability to walk and swallow, making it a progressive degenerative disorder primarily affecting the nervous system rather than specifically causing abdominal pain, visual impairment, or fatigue to a prominent extent. Therefore, while headache can occur, the more notable signs are related to coordination and motor function, indicating the complex nature of Kuru's clinical manifestations.