What is the duration of the incubation period for Kuru?

The incubation period for Kuru is typically 5-20 years, which points to a longer duration than many other infectious diseases. Kuru is a rare and fatal neurological disorder caused by prion infection, primarily seen among the Fore people of Papua New Guinea due to their practice of ritualistic cannibalism. The long incubation period reflects the slow progression of prion diseases, as the abnormal proteins accumulate in the brain over time before symptoms manifest. This characteristic is especially important in understanding both the transmission dynamics of the disease and its historical context within the Fore community. The awareness of such long incubation periods helps emphasize the challenges associated with prion diseases and their effects on cultural practices.